BIOcoretheorySem 3
DOWNSTREAM PROCESSING-II
BIO 3124
Syllabus
- 01Theories of adsorption – Adsorption isotherms and calculations, and models, adsorption in fixed beds, Pressure Swing Adsorption (PSA)
- 02Chromatography – principles of chromatographic separation and Plate theory, HPLC and GC, Various types of Chromatographic practices, Retention time, Capacity, band broadening, Size exclusion, Ion Exchange and Affinity chromatography
- 03Electrophoresis
- 04Crystallization, Supersaturation, Yield Calculation, Meir's and Oswald's Theorems
- 05Drying-theory, Equilibrium and batch drying curve, calculations
References
- Roger Harrison, Paul Todd, Scott Rudge and Demetri Petrides, Bioseparations Science and Engineering, Oxford University Press, 87 2nd Edition, 2003
- Belter P.A., Cussler E. and Wei Shan Hu. Bioseparation – Downstream processing for biotechnology, Wiley Interscience Pub, 1988.
- Asenjo J. and Dekker M, Separation Processes in Biotechnology, CRC Press, 2020.
- McCabe & Smith, Unit Operations of Chemical Engineering, McGraw Hill Inc, 7th Edition , 2017
- R.E. Treybal, Mass transfer, McGraw Hill, 1981
Credits Structure
2Lecture
1Tutorial
0Practical
3Total